Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis

Table 6 Multivariate ordered logistic regression analysis determining role of genetic polymorphisms in increasing hepatic fibrosis stage

Gene	OR	95%CI	P value	Adjusted P value1
MCP1	1.11	0.69-1.80	0.660	0.681
CCR2	0.71	0.36-1.32	0.284	0.432
TGFβ	1.03	0.54-1.95	0.936	0.740
hOGG1	0.94	0.44-1.98	0.864	0.588
IL10-1082	1.10	0.65-1.88	0.720	0.897
IL10-592	0.82	0.50-1.35	0.441	0.639
TLR4 299	0.73	0.35-1.53	0.403	0.745
TLR4 399	0.87	0.42-1.81	0.706	0.990

¹Adjusted for age at biopsy: gender: iron grade and alcohol consumption. MCP-1: Monocyte chemoattractant protein 1; CCR-2: Chemokine C-C motif receptor; IL10: Interleukin-10; TGF-β: Transforming growth factor-beta; TLR4: Toll-like receptor 4; hOGG1: Human 8-oxoguanine DNA glycosylase.