Topic Highlight
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2013; 19(48): 9174-9182
Published online Dec 28, 2013. doi: 10.3748/wjg.v19.i48.9174
Table 1 Studies reporting the negative impact of increased neutrophil-to-lymphocyte ratio measured at transplant on the outcome of liver transplantation for hepatocellular carcinoma
Ref.Patients (n)Type of LTNLR cut-off level for poor prognosisOther factors associated with worse outcome5-yr RFS with high vs low NLR5-yr OS with high vs low NLRParameters positively correlated with increased NLR
Halazun et al[15]150NA5Tumor sizeAFP25% vs 75%128% vs 64%None
Bertuzzo et al[16]219DDLT5Microvascular invasion6% vs 89%14% vs 73%Micro/macro vascular invasionTumor gradingAFPCRPOutside MC
Wang et al[17]101DDLT3Tumor numberMacrovascular invasion28% vs 65%119% vs 62%Macrovascular invasionAFPTumor sizeOutside MCOutside UCSF criteriaOutside Hangzhou criteria
Limaye et al[18]160NA5Microvascular invasion AFP27% vs 79%38% vs 68%None
Motomura et al[19]158LDLT4Outside MC30% vs 89%57% vs 84%Serum/peritumoral IL-17Density of peritumoral CD163CRPTacrolimus vs cyclosporine
2Yoshizumi et al[20]104LDLT4Nodule size + number ≥ 8.042% vs 86%Not reportedMicrovascular invasionTumor grading