Routine lymph node dissection may be not suitable for all intrahepatic cholangiocarcinoma patients: Results of a monocentric series

Table 4 Selected published series of intrahepatic cholangiocarcinoma patients after resection

Author	Year	Cases	Prognostic factors	Median survival time	5-yr survival rate	Routine LND
Ribero et al[8]	2012	434	LN metastases	33	32.90%	No
			Multiple tumors
			CA19.9 level
de Jong et al[9]	2011	449	Tumor number	27.3	30.7	No
			Vascular invasion
			LN metastasis
Saxena et al[26]	2010	88	CA 19.9 level	33	28	No
			Clinical stage
			Histological grade
			LN metastases
Ercolani et al[27]	2010	72	LN metastasis	57.1	48	Yes
			Blood transfusion
Cho et al[28]	2010	63	Old age	Not available	31.8	Yes
			CA19-9 level
			LN metastasis
			Narrow resection margin
Shirabe et al[29]	2010	60	Lymphatic invasion index	Not available	30.6	No
			Histological grade
Guglielmi et al[30]	2009	81	LN metastasis	40	20	Not available
			Vascular invasion
Tamandl et al[31]	2009	93	Lymph node ratio	25.5	Not available	No
Choi et al[37]	2009	64	LN metastasis	39	39.5	No
Shimada et al[32]	2009	104	Intrahepatic metastases	25	37	No
			LN metastasis
Yedibela et al[33]	2009	67	Resection margin	26	27	No
			LN metastasis
			Blood transfusion
Nakagohri et al[34]	2008	56	Intrahepatic metastasis	22	32	Not available
Uenishi et al[35]	2008	133	Intrahepatic metastasis	18.4	29	Yes
			LN metastases
			Tumor at the margin
Shimada et al[36]	2007	57	LN metastasis	62	56.8	No

LN: Lymph node; LND: Lymph node dissection; ICC: Intrahepatic cholangiocarcinoma.