Is Dor fundoplication optimum after laparoscopic Heller myotomy for achalasia? A meta-analysis

Table 5 Pooled outcomes of random controlled studies and non-random controlled studies for postoperative physiological testing and operation-related data

	Studies (n)	Participants		Test of heterogeneity		MD (95%CI)	P value for effect size
		Dor group	Control group	I2	P value
LES pressure
Dor-other group	2	47	43	94%	< 0.0001	-1.02 (-9.90, 7.86)	0.821
Dor-no group	2	58	43	65%	0.09	1.97 (-0.93, 4.86)	0.182
DeMeester score
Dor-other group	2	40	39	48%	0.17	-7.13 (-18.37, 4.12)	0.212
Dor-no group	1	21	18	Not applicable		-25.00 (-58.40, 8.40)	0.14
Percent total time pH ≤ 4
Dor-other group	4	154	142	63%	0.05	0.96 (0.00, 1.91)	0.051
Dor-no group	1	21	18	Not applicable		-7.20 (-13.34, -1.06)	0.02
Surgery time
Dor-other group	3	138	122	14%	0.31	-5.37 (-7.71, -3.03)	< 0.000012
Dor-no group	2	39	36	0%	0.35	24.14 (7.21, 41.08)	0.0052
Hospital stay time
Dor-other group	4	171	176	94%	< 0.00001	0.10 (-0.59, 0.80)	0.771
Dor-no group	1	22	21	Not applicable		0.00 (-0.15, 0.15)	1.00

¹Random-effect model;

²Fixed-effect model. RCT: Random controlled trial.