Advances in the management of acute liver failure

Table 1 Drugs which may cause idiosyncratic liver injury leading to acute liver failure

Classification	Drugs
Anti-infective agents	Amoxicillin/clavulanateerythromycin, roxithromycin, telithromycin, doxycycline, minocyclinenitrofurantoin, ciprofloxacin, levofloxacin, moxifloxacintrimethoprim-sulfamethoxazole, sulfasalazine, isoniazid, rifampin, pyrazinamide, ethambutol, dapsone,fluconazole, itraconazole, terbinafine, ketoconazole, chloroquineDidanosine, fialuridine, efavirenz, abacavir, nevirapine-lamivudine
Cardiovascular agents	Amiodarone, labetalol, diltiazem, methyldopa, valsartan, lisinopril, angiotensin converting enzyme inhibitorAsparaginase, flutamide
Hypolipidemic agents	Atorvastatin, cerivastatin, simvastatin, pravastatin, fluvastatin, ezetimibe
Hypoglycemic Agents	Metformin, troglitazone
Anti-allergic agents	Zafirlukast, loratadine, diphenhydramine
Herbal products/dietary supplements	Kava, Herbalife, Comfrey, Senecio, Greater Celandine, Polygonum multiflorum, ginseng, Teucrium polium, usnic acid, ma huang, Chaso, Onshido, Hydroxycut, LipoKinetix
Neurological and psychiatric drugs	Halothane, isoflurane, butorphanolopiates, amphetamines, marijuana, cocainePhenytoin, valproic acid, carbamazepine, felbamate, lamotrigine, vigabatrinamitriptyline, imipramine, sertraline, paroxetine, venlafaxine, pemoline, bupropionChlorpromazine, quetiapine, clonazepamtolcapone
Nonsteroidal anti-inflammatory drugs	Diclofenac, bromfenac, etodolac, naproxen, ibuprofen, indometacin
Miscellaneous	Propylthiouracil, retinol, infliximab, allopurinol, cyclosporine, disulfiram, iron sulfate, anabolic steroids, carbon tetrachloride, phenprocoumon, nicotinic acid
Antineoplastic agents	Methotrexate, cytoxan, etoposide, dactinomycin, azathioprine, tamoxifen