Overexpression of nuclear β-catenin in rectal adenocarcinoma is associated with radioresistance

Table 2 Univariate and multivariate regression analyses of the association of clinical features with radiotherapy response of rectal adenocarcinoma n (%)

Clinicopathological factors	Univariate analysis		Multivariate analysis
	Good response1	P value	OR	P value
Gender
Male	15 (13.8)	0.697		NS
Female	3 (10.7)
Age (yr)
≤ 55	5 (26.3)	0.129		NS
> 55	13 (11.1)
Tumor size (cm)
≤ 5	16 (20.5)	< 0.001	5.058	< 0.001
> 5	2 (3.5)
Tumor cell differentiation
Well/moderately differentiated	4 (4.1)	< 0.001	4.692	< 0.001
Poorly differentiated	14 (36.8)
Tumor invasion depth
T1/T2	7 (30.4)	0.027	1.143	0.053
T3/T4	11 (9.7)
Nuclear β-catenin expression
≤ 50%	15 (23.1)	< 0.001	6.375	< 0.001
> 50%	3 (4.2)

¹Tumor regression grading ≥ 3. NS: Not selected.