Overexpression of nuclear β-catenin in rectal adenocarcinoma is associated with radioresistance

Table 1 Correlation of nuclear β-catenin expression in rectal adenocarcinoma with clinicopathologic characteristics

Characteristics	n	Nuclearβ-catenin expression		P value1
		≤50%	> 50%
Gender
Male	108	54	54	0.312
Female	28	11	17
Age (yr)
≤ 55	19	11	8	0.342
> 55	117	54	63
Tumor size (cm)
≤ 5	78	38	40	0.802
> 5	58	27	31
Tumor cell differentiation
Well/moderately differentiated	98	53	45	0.018
Poorly differentiated	38	12	26
Tumor invasion depth
T1/T2	23	15	8	0.066
T3/T4	113	50	63
Lymph node metastasis
N1	74	42	32	0.022
N2	62	23	39
TRG
TRG0-2	118	50	68	< 0.001
TRG3-4	18	15	3

¹Value is the result of χ² test in the same factor, and P < 0.05 is considered significant statistically. TRG: Tumor regression grading.