Age-dependent slowing of enteric axonal transport in insulin-resistant mice

Figure 1 Cartoon of ascending, descending and local enteric pathways in the stomach. Enteric nerve terminals endocytosed the tracer fluorogold (small green circles) and it was transported back to cell bodies (large green circles) located in the fundus, corpus, or antrum. A: The retrograde tracer fluorogold was injected into the fundus. Red neurons were in the ascending pathway while blue neurons were in the local fundic pathway. The approximate distances from fundus injection sites were 0.6, 2.2, and 3.3 cm for fundus, corpus, and antrum sections, respectively; B: The retrograde tracer fluorogold was injected into the antrum. Purple neurons were in the descending pathway while blue neurons were in the local antral pathway. The approximate distances from antrum injection sites were 3.2, 1.1, and 0.4 cm for fundus, corpus, and antrum sections, respectively.