Anisodamine accelerates spontaneous passage of single symptomatic bile duct stones ≤ 10 mm

Table 1 Baseline characteristics of patients n (%)

	Control group	Anisodamine group	P value
	(n = 97)	(n = 100)
Age (yr)	59.1 ± 10.9	58.0 ± 12.4	0.564
Sex			0.422
Male	42 (43.3)	49 (49.0)
Female	55 (56.7)	51 (51.0)
Main presentations
Biliary colic	40 (41.2)	44 (44.0)	0.695
Cholangitis	25 (25.8)	27 (27.0)	0.845
Jaundice	20 (20.6)	19 (19.0)	0.776
Acute pancreatitis	12 (12.4)	10 (10.0)	0.597
Median time interval from symptom onset to hospital admission			0.606
< 24 h	84 (86.6)	89 (89.0)
≥ 24 h and ≤ 48 h	13 (13.4)	11 (11.0)
Imaging methods for diagnosis			0.918
Conventional CT	82 (84.5)	84 (84.0)
MRCP	15 (15.5)	16 (16.0)
Median diameter of CBD stone	0.54 ± 0.24	0.55 ± 0.24	0.837
Minimum, mm	0.3	0.3
Maximum, mm	1.0	1.0
Diameter of CBD stone			0.959
< 5 mm	44 (45.4)	45 (45.0)
≥ 5 mm and ≤ 10 mm	53 (54.6)	55 (55.0)	.
Median diameter of CBD	12.6 ± 4.3	12.9 ± 3.8	0.683
Minimum, mm	8.0	8.3
Maximum, mm	23.0	25.0
History of cholecystectomy			0.856
Yes	27 (27.8)	29 (29.0)
No	70 (72.2)	71 (71.0)

CT: Computed tomography; CBD: Common bile duct; MRCP: Magnetic resonance cholangiopancreatography.