HER2 in gastric cancer: Comparative analysis of three different antibodies using whole-tissue sections and tissue microarrays

doi:10.3748/wjg.v19.i38.6438

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2013; 19(38): 6438-6446
Published online Oct 14, 2013. doi: 10.3748/wjg.v19.i38.6438

Table 3 Human epidermalgrowth factor receptor 2 gene status assessed by dual-color in situ hybridization in cases with an immunohistochemistry score of 2+ with HercepTest, 4B5 and SP3 staining on whole-tissue sections and tissue microarrays n (%)

HER2gene status	Whole-tissue sections			TMAs
HER2gene status	HercepTest	4B5	SP3	HercepTest	4B5	SP3
Amplified	0 (0)	6 (30)	6 (17.6)	3 (75)	3 (100)	4 (26.6)
Not amplified	1 (100)	14 (70)	28 (82.4)	1 (25)	0 (0)	11 (73.4)
Total	1 (100)	20 (100)	34 (100)	4 (100)	3 (100)	15 (100)

TMA: Tissue microarray; HER2: Human epidermalgrowth factor receptor 2.

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Citation: Abrahão-Machado LF, Jácome AADA, Wohnrath DR, Santos JSD, Carneseca EC, Fregnani JHTG, Scapulatempo-Neto C. HER2 in gastric cancer: Comparative analysis of three different antibodies using whole-tissue sections and tissue microarrays. World J Gastroenterol 2013; 19(38): 6438-6446
URL: https://www.wjgnet.com/1007-9327/full/v19/i38/6438.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i38.6438

Abrahão-Machado LF, Jácome AADA, Wohnrath DR, Santos JSD, Carneseca EC, Fregnani JHTG, Scapulatempo-Neto C. HER2 in gastric cancer: Comparative analysis of three different antibodies using whole-tissue sections and tissue microarrays. World J Gastroenterol 2013; 19(38): 6438-6446 [PMID: 24151362 DOI: 10.3748/wjg.v19.i38.6438]

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