In vitro effect of amoxicillin and clarithromycin on the 3&rsquo; region of cagA gene in Helicobacter pylori isolates

doi:10.3748/wjg.v19.i36.6044

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Sep 28, 2013 (publication date) through Apr 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2013; 19(36): 6044-6054
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6044

Table 3 Detection of cag pathogenicity island in Helicobacter pylori isolates resistant in baseline and in antibiotic dilutions by amplification of the cagA gene n (%)

Method	*Detection of the cag* PAI**
		Dilutions
	Baseline	Amoxicillin	Clarithromycin
	(n = 13)	(n = 32)	(n = 28)
cagA PCR	11 (84.6)	30 (93.8)	22 (78.6)
EPIYA PCR	12 (92.3)	20 (62.5)	16 (57.1)
P value	> 0.05	0.006	0.031

PAI: Pathogenicity island; PCR: Polymerase chain reaction; EPIYA: Glu-Pro-Ile-Tyr-Ala.

Citation: Bustamante-Rengifo JA, Matta AJ, Pazos A, Bravo LE. In vitro effect of amoxicillin and clarithromycin on the 3’ region of cagA gene in Helicobacter pylori isolates. World J Gastroenterol 2013; 19(36): 6044-6054
URL: https://www.wjgnet.com/1007-9327/full/v19/i36/6044.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i36.6044