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©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 7, 2013; 19(33): 5500-5507
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5500
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5500
Figure 3 Fucoidan prevented H2O2-induced increases in paracellular permeability.
First, 0.5 mg/mL 4-kDa FITC-labeled dextrans (FD4) were added into the apical well and cultured for 6 h with or without H2O2 (500 μmol/L) and/or fucoidan (2.5 mg/mL). After 6 h of incubation, the basal medium was collected, and the fluorescence was measured as fluxed-FD4. H2O2-induced FD4 flux was considered 100%. The data are expressed as the means ± SEM of 5 independent experiments. bP < 0.01 (Student’s t test).
- Citation: Iraha A, Chinen H, Hokama A, Yonashiro T, Kinjo T, Kishimoto K, Nakamoto M, Hirata T, Kinjo N, Higa F, Tateyama M, Kinjo F, Fujita J. Fucoidan enhances intestinal barrier function by upregulating the expression of claudin-1. World J Gastroenterol 2013; 19(33): 5500-5507
- URL: https://www.wjgnet.com/1007-9327/full/v19/i33/5500.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i33.5500