HLA class II associated with outcomes of hepatitis B and C infections

Table 2 Single nucleotide polymorphisms within human leukocyte antigen loci associated with outcomes of hepatitis C virus infection

Ethnic group	Outcome	No. of cohorts	HLA locus	SNP	Odds	95%CI	Haplotype	Odds	Ref.
Japanese	HCC	721 HCC vs 2890 HCV-negative controls	MICA	rs2596542	1.34	1.16-1.53			[30]
Japanese	Cirrhosis	682 cirrhosis vs 1045 Chronic hepatitis	C6orf10	rs910049	1.73	1.40-2.15			[31]
			No gene	rs3135363	1.58	1.32-1.90
							DQA1*0601	2.80
							DPB1*0405	1.45

SNP: Single nucleotide polymorphism; HCC: Hepatocellular carcinoma; HLA: Human leukocyte antigen; HCV: Hepatitis C virus.