Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia

Table 1 Clinical and histo-pathological characteristics of the 51 colorectal cancer patients n (%)

Characteristic	Patient
Age of onset of the first cancer (range) (yr)	51 (17-85)
≤ 50	25 (49.0)
> 50	26 (51.0)
Sex
Male	30 (58.8)
Female	21(41.2)
Site of the first CRC
Right colon	14 (27.5)
Left colon	16 (31.4)
Rectum	21 (41.2)
TNM tumor stage
I	3 (5.9)
II	24 (47.1)
III	20 (39.2)
IV	3 (5.9)
Others	1 (2.0)
Degree of differentiation
Well	33 (64.7)
Moderate	14 (27.5)
Poor	2 (3.9)
Mucinous CRC	2 (3.9)
Mucinous carcinoma type
≥ 50%	14 (27.5)
≤ 50%	37 (72.5)
Signet ring cell carcinoma	2 (3.9)
Tumor infiltrating lymphocyte
Crohn’s–like reaction	2 (3.9)
Intra epithelial lymphocytes	1 (2.0)
Lymphoïde peritumoral reaction	10 (19.6)
Synchronous CRC	3 (5.9)
Metachronous CRC and HNPCC related cancer	3 (5.9)
Fulfillment of guidelines
Amsterdam	3 (5.9)
Revised Bethesda	22 (43.1)
B1	22
B2	3
B3	11
B4	1
B5	1

CRC: Colorectal cancer; HNPCC: Hereditary nonpolyposis colorectal cancer; TNM: Tumor node metastasis.