Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy

Table 3 SpO₂, blood pressure, and pulse rate during the endoscopy procedure (mean ± SD)

Group	Time	SpO2 (%)	SBP (mmHg)	DBP (mmHg)	P (bpm)
Cs	Before	98.1 ± 1.6	126.0 ± 11.2	80.7 ± 6.7	74.4 ± 13.7
(n = 43)	During	95.8 ± 6.0b	115.6 ± 11.9b	72.8 ± 6.6b	73.8 ± 14.0
	After	98.0 ± 1.6	124.9 ± 11.3b	79.1 ± 6.5b	74.2 ± 14.1
Cc	Before	98.0 ± 1.8	128.5 ± 11.0	80.5 ± 5.6	77.2 ± 14.3
(n = 43)	During	90.7 ± 13.6b	113.5 ± 9.4b	71.0 ± 4.9b	75.0 ± 14.3b
	After	97.3 ± 2.6b	126.3 ± 11.0b	78.5 ± 5.8b	76.6 ± 14.5
Ns	Before	98.2 ± 1.8	130.2 ± 5.0	82.0 ± 4.1	73.7 ± 13.7
(n = 41)	During	96.5 ± 5.0a	120.0 ± 5.2b	74.3 ± 4.4b	73.0 ± 13.7
	After	98.1 ± 1.7	127.9 ± 5.0b	80.0 ± 4.3b	73.4 ± 13.6
Nc	Before	98.2 ± 1.8	127.8 ± 9.3	81.4 ± 2.6	70.4 ± 12.7
(n = 41)	During	95.6 ± 6.7b	117.1 ± 8.7b	73.5 ± 2.9b	69.0 ± 12.3b
	After	98.1 ± 1.7	125.5 ± 8.9b	79.0 ± 2.7b	70.4 ± 12.5

Group Cs: Chronic obstructive pulmonary disease (COPD) with stepwise sedation; Group Cc: COPD with continuous sedation; Group Ns: Non-COPD with stepwise sedation; Group Nc: Non-COPD with continuous sedation; SpO₂: Saturation of peripheral oxygen; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; P: Pulse rate.

^aP < 0.05,

^bP < 0.01 vs before the endoscopy.