Fibroblast growth factor receptor 4 Gly388Arg polymorphism in Chinese gastric cancer patients

Table 3 Association analysis of the fibroblast growth factor receptor 4 Gly388Arg polymorphism and clinicopathological parameters in gastric cancer patients

Variables	Totaln = 304	Gly/Glyn = 118	Gly/Arg + Arg/Argn = 186	Pearson’sχ2value	P value
Age (yr)				0.013	0.909
< 60	125	49	76
≤ 60	179	69	110
Sex				1.398	0.237
Male	223	91	132
Female	81	27	54
Tumor size				0.198	0.656
≤ 3 cm	58	24	34
> 3 cm	246	94	152
Differentiation				2.122	0.145
G1 + G2	100	33	67
G3 + G4	204	85	119
Invasion depth				0.000	0.995
T1 + T2	49	19	30
T3 + T4	255	99	156
N stage				0.640	0.200
N0	82	27	55
N1 + N2 + N3	222	91	131
M stage				1.089	0.297
M0	274	109	165
M1	30	9	21
Clinical stage				0.980	0.322
I + II	103	36	67
III + IV	201	82	119
HER2 status				0.391	0.532
Negative	180	63	117
Positive	45	18	27

FGFR4: Fibroblast growth factor receptor 4; GC: Gastric cancer; HER2: Human epidermal growth factor receptor 2.