Different regional distribution of SLC25A13 mutations in Chinese patients with neonatal intrahepatic cholestasis

Table 2 Conservation analysis of SLC25A13 gene mutations F96S and E450G among different species

F96S

Human

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Canis

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Bos

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Equus

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Pan

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Mus

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Gallus

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

Xenopus

L

C

A

P

D

A

L

F

M

V

A

F

Q

L

F

D

K

A

G

K

G

E

V

E450G

Human

G

G

S

Q

V

I

F

T

N

P

L

E

I

V

K

I

R

L

Q

V

A

G

E

Canis

G

G

S

Q

V

I

F

T

N

P

L

E

I

V

K

I

R

L

Q

V

A

G

E

Bos

G

G

S

Q

V

I

F

T

N

P

L

E

I

V

K

I

R

L

Q

V

A

G

E

Equus

G

G

S

Q

V

I

F

T

N

P

L

E

I

V

K

I

R

L

Q

V

A

G

E

Pan

G

G

S

Q

V

I

F

T

N

P

L

E

I

V

K

I

R

L

Q

V

A

G

E

Mus

G

G

S

Q

V

I

F

T

N

P

L

E

I

V

K

I

R

L

Q

V

A

G

E

Gallus

G

M

C

Q

V

V

F

T

N

P

L

E

I

V

K

I

R

L

Q

T

A

G

E