Reversal of multidrug resistance in gastric cancer cells by CDX2 downregulation

doi:10.3748/wjg.v19.i26.4155

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Jul 14, 2013 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2013; 19(26): 4155-4165
Published online Jul 14, 2013. doi: 10.3748/wjg.v19.i26.4155

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Figure 2 Effect of downregulation of CDX2 on cell pump rate of doxorubicin, cell cycle, and apoptotic rate in SGC7901/DDP cells after RNA interference. A, B: Pump rate of doxorubicin in SGC7901/DDP cells after RNAi was analyzed by flow cytometry; C, D: Cell cycle in SGC7901/DDP cells after RNAi was analyzed by flow cytometry; E, F: Apoptotic rate in SGC7901/DDP cells after RNAi was analyzed by flow cytometry. ^aP < 0.05 for SGC7901/DDP + small interfering RNA (siRNA)-CDX2 cells vs SGC7901/DDP + siRNA-NC cells and SGC7901/DDP cells. Lane 1: SGC7901/DDP + siRNA-CDX2 cells; Lane 2: SGC7901/DDP + siRNA-NC cells; Lane 3: SGC7901/DDP cells.

Citation: Yan LH, Wang XT, Yang J, Lian C, Kong FB, Wei WY, Luo W, Xiao Q, Xie YB. Reversal of multidrug resistance in gastric cancer cells by CDX2 downregulation. World J Gastroenterol 2013; 19(26): 4155-4165
URL: https://www.wjgnet.com/1007-9327/full/v19/i26/4155.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i26.4155