Cytokine profiles in patients receiving antioxidant therapy within the ANTICIPATE trial

Table 3 Antioxidant profiles at 6 mo compared to baseline

Variables	Antioxidant (n = 7)	Placebo (n = 7)	P value (antioxidant vs baseline)	95%CI	P value (antioxidant vs placebo )	95%CI
Vitamin C (μg/mL)	17.6 (12.8-29.3)	4.8 (1.6-9.1)	0.001	-18.8-6.5	< 0.001	9.0-20.2
Vitamin E (mg/L)	17.8 (11.7-25.0)	5.0 (4.0-4.6)	0.160	-1.8-12.3	0.004	4.4-14.3
β-carotene (mol/L)	155.5 (23-478)	38.1 (8-204)	0.150	-189-35	0.244	-20-190
Vitamin A (mg/L)	0.5 (0.42-0.72)	0.3 (0.25-0.64)	0.910	-0.19-0.14	0.010	0.05-0.34
Selenium (μg/L)	109 (95-133)	48 (40-92)	0.007	-75-14	< 0.001	41-85
WCC (109/L)	6.7 (4.9-10.8)	7.4 (6-10.8)	0.330	-1.3-3.2	0.600	-3.3-1.9
Hb (g/dL)	14.2 (13.5-16.0)	12.7 (12.3-16.0)	0.510	-1-1.6	0.150	-1.3-2.6
CRP (mg/L)	3 (3-4)	6 (3-10)	0.190	0-3	0.070	-7-0
Opiate usage	20	55	0.210	-40-79	0.630	-56-60

WGSH: Whole blood glutathione; WGSH/Hb: Glutathione corrected for haemoglobin concentration; WCC: White cell count; Hb: Haemoglobin; CRP: C-reactive protein.