Human leukocyte antigen DQ2/8 prevalence in non-celiac patients with gastrointestinal diseases

Table 2 Prevalence of human leukocyte antigen DQ2/8 by age, gender and gastrointestinal disease

	Proportion of positive subjects	Prevalence	P value
Overall	196/443	44.2%	0.02
Gender1
Male	92/199	46.2%
Female	104/244	42.6%	0.45
Age (yr)
14-41	48/108	44.4%
42-56	42/111	37.8%
57-65	53/107	49.5%
66-85	52/114	45.6%	0.37
Disease groups
Liver	86/188	45.7%
Upper functional	39/73	53.4%
Upper organic	19/41	46.3%
IBS	38/105	36.2%
IBD	14/36	38.9%	0.21

¹P > 0.05 for differences between genders in each disease group except for those with upper functional disorders. In these patients significantly more males were positive than females (P = 0.05). IBS: Irritable bowel syndrome; IBD: Inflammatory bowel disease.