Habitual rapid food intake and ineffective esophageal motility

Table 1 Esophageal manometry results, expressed as mean (95%CI) in ineffective esophageal motility patients and healthy controls

	IEM patients with the habit of fast eating (n = 12)	IEM patients without the habit of fast eating (n = 7)	Healthy controls (n = 10)
LES pressure (mmHg)	12.71 (6.80-18.62)	11.08 (-0.59-22.76)	14.94 (10.38-19.49)
Distal esophagus
Amplitude (mmHg)	28.29 (21.77-34.81)b	33.78 (19.56-48.00)	50.75 (38.44-63.05)
Duration (s)	3.04 (2.44-3.65)	2.74 (1.32-4.15)	3.09 (2.30-3.88)
Velocity (cm/s)1	1.42 (1.14-1.70)	3.33 (0.79-5.86)	1.57 (0.89-2.24)
Mid esophagus
Amplitude (mmHg)	23.45 (14.06-32.85)b	30.09 (19.48-40.70)a	58.80 (42.56-75.04)
Duration (s)	3.12 (2.32-3.91)	3.18 (1.81-4.55)	2.45 (2.13-2.79)
Velocity (cm/s)2	2.18 (1.23-3.12)	3.76	2.35 (1.38-3.33)
Proximal esophagus
Amplitude (mmHg)	36.75 (22.93-50.57)	41.47 (8.79-74.15)	49.96 (36.28-63.64)
Duration (s)	2.42 (1.84-3.00)	3.13 (1.48-4.77)	2.25 (1.80-2.71)
Velocity (cm/s)3	3.66 (1.71-5.60)	2.56	2.42 (1.75-3.09)

¹Velocity in the distal esophagus of 3 fast-eating and 3 normal-eating IEM patients could not be calculated due to simultaneous contractions; ^2,3Velocity in the mid (proximal) esophagus of 6 fast-eating and 5 normal-eating IEM patients and 2 healthy controls could not be calculated due to simultaneous contractions. Contraction data were in response to wet swallows. Data indicative of simultaneous (i.e., velocity > 8 cm/s) or other non-propulsive contraction were excluded when calculating the mean velocity.

^aP < 0.05,

^bP < 0.01 vs control. IEM: Ineffective esophageal motility; LES: Lower esophageal sphincter.