Clinical application of microRNA in gastric cancer in Eastern Asian area

Table 1 microRNA expression in gastric cancer in 2008-2012

Group	Method	Sample	Upregulated	Downregulated
Katada et al[29]	TaqManmiRNA assays + qRT-PCR	42 undifferentiated gastric cancer and controls	miR-34b miR-34c miR-128a	miR-128b, miR-129, miR-148
Guo et al[30]	Microarray	3 gastric cancers and adjacent normal tissues	miR-20b, miR-20a, miR-17, miR-106a, miR-18a, miR-21, miR-106b, miR-18b, miR-421, miR-340, miR-19a, miR-658	miR-768-3p, miR-378, miR-31, miR-139-5p, miR-195, miR-497, miR-133b,
Yao et al[31]	Microarray + qRT-PCR	10 gastric cancers and adjacent normal tissue	miR-223, miR-106b, miR-147, miR-34a, miR-130b, miR-106a, miR-18a, miR-17, miR-98, miR-616,miR-181a-2, miR-185, miR-1259, miR-601, miR-196a, miR-221, miR-302f, miR-340, miR-337-3p, miR-520c-3p, miR-575 and miR-138	miR-638, miR-378
Luo et al[32]	Microarray + qRT-PCR	24 gastric cancers	MiR-26b, miR-30a-5p, miR-212, miR-320, miR-379, miR-518b, miR-409-3b	MiR-9, miR-19b, miR-155, miR-188, miR-197, miR-338, miR-370, miR-383, miR-433, miR-490, miR-503, miR-545, miR-551a, miR-567, miR-575, miR-611, miR-630, miR-649, miR-652
Ueda et al[33]	Microarray + qRT-PCR	353 (184 gastric cancers 169 controls)	miR-181d, miR-181a-1, miR-181a-2, miR-181c, miR-181b-1, miR-181b-2, miR-21, miR-25, miR-92-1, miR-92-2, miR-93, miR-17-5p, miR-106a, miR-20b, miR-135a-1, miR-135a-2, miR-425-5p, miR-106b, miR-20a, miR-19b-1, miR-19b-2	miR-148a, miR-148b, miR-375, miR-29b-1, miR-29b-2, miR-29c, miR-152, miR-218-2miR-451, miR-30d
Tsukamoto et al[34]	Microarray (470) + qRT-PCR	22 gastric cancers	miR-18a, miR-106a, miR-17, miR-146a, miR-93, miR-19a, miR-20a, miR-20b, miR-25, miR-15b, miR-425, miR-92a, miR-194, miR-10a, miR-222, miR-7, miR-106b, miR-320a, miR-21, miR-34a, miR-19b, miR-103, miR-215, miR-192, miR-429, miR-27a, miR-223, miR-23a, miR-107, miR-200b, miR-24, miR-15a, miR-16	miR-375, miR-29c, miR-148a, miR-30a-5p, miR-30e-5p, miR-638
Li et al[35]	TaqManmiRNA assays + qRT-PCR	30 gastric cancer and controls	miR-223, miR-21, miR-23b, miR-222, miR-25, miR-23a, miR-221, miR-107, miR-103, miR-99a, miR-100, miR-125b, miR-92, miR-146a, miR-214 and miR-191,	let-7a, miR-126, miR-210, miR-181b, miR-197, miR-30aa-5p
Carvalho et al[36]	Microarray + qRT-PCR	76 gastric cancers	miR-582-5p, miR-151-5p, miR-296-5p, miR-30b, miR-513-5p, miR-335, miR-576-5p, miR-219-2-3p, miR-331-5p, miR-889, miR-152, miR-992, miR-93, miR-519c, miR-599, miR-520a-5p, miR-631, miR-550, miR-136, miR-22, miR-515-5p, miR-127-3p, miR-374a, miR-181a, miR-192, miR-532-3p, miR-30d, miR-640, miR-425, miR-92b, miR-501-5p, miR-514, miR-576-3p, miR-519e, miR-149, miR-219-1-3p, miR-424, miR-220, miR-96, miR-218-2, miR-649, miR-215, miR-182, miR-122, miR-524-3p, miR-187, miR-526b, miR-770-5p, miR-545, miR-200b, miR-9, miR-141, miR-579, miR-493, miR-137, miR-216a, miR-503, miR-126, miR-23b, miR-99b, miR-101, miR-323-3p, miR-25, miR-92a-1, miR-429	miR-451, miR-502-3p, miR-101 miR-33a, miR-516a-3p/miR-516b

qRT-PCR: Quantitative reverse transcriptase polymerase chain reaction.