Evaluation of the relationship between dietary factors, CagA-positive Helicobacter pylori infection, and RUNX3 promoter hypermethylation in gastric cancer tissue

Table 2 Distribution of age, gender, Helicobacter pylori infection, CagA status, and RUNX3 expression according to RUNX3 methylation status n (%)

Variables	RUNX3 methylation (+)	RUNX3 methylation (-)	P value
Age (mean ± SD), yr	60.5 ± 11.2	58.7 ± 11.5	0.290
Gender			0.648
Male	70 (56.5)	36 (67.4)
Female	54 (43.5)	24 (40.0)
Helicobacter pylori infection			0.234
Negative	14 (13.2)	6 (7.7)
Positive	92 (86.8)	72 (92.3)
CagA status			0.997
Negative	72 (67.9)	53 (68.0)
Positive	34 (32.1)	25 (32.0)
RUNX3 expression			0.007
Positive	34 (46.6)	33 (71.7)
Negative	39 (53.4)	13 (28.3)