Brief Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2012; 18(8): 814-820
Published online Feb 28, 2012. doi: 10.3748/wjg.v18.i8.814
Table 3 Germline mutations of MSH2 gene detected in 4/34 Lynch syndrome patients
GenePatients IDAgeExon/intron regionNucleotide changeConsequence
MSH2LS850Exon 12c.2005G > CMissense mutation (G669R)
LS2043Exon 12c.2005G > CMissense mutation (G669R)
LS3741Intron 12c.2006-6T > CSplice-site mutation
LS4149Exon 1c.142G > TNonsense mutation (E48X)