Itopride therapy for functional dyspepsia: A meta-analysis

Table 1 Clinical data of included articles

Ref.	Year	Quality grade	Total cases	Duration of therapy (wk)	Treatment group			Control group
					Cases(male/female)	Average age (yr)	Itopride dosing regimen	Cases (male/female)	Average age (yr)	Dosing regimen
Zhou et al[14]	2000	B	208	2	105	43	50 mg tid	103	46	Domperidone 10 mg tid
Sun et al[15]	2003	B	232	2	115	-	50 mg tid	117	-	Domperidone 10 mg tid
Mo et al[16]	2003	B	80	2	40	-	50 mg tid	40	-	Domperidone 10 mg tid
Chen et al[17]	2004	B	42	4	21	35	50 mg tid	21	36	Domperidone 10 mg tid
Amarapurkar et al[18]	2004	B	60	2	30 (19/11)	45	50 mg tid	30 (11/19)	40	Mosapride 5 mg tid
Zhu et al[19]	2005	B	236	4	119	-	50 mg tid	117	-	Domperidone 10 mg tid
Li et al[20]	2005	B	200	4	100 (47/53)	38	50 mg tid	100 (47/53)	38	Domperidone 10 mg tid
Holtmann et al[13]	2006	A	412	8	50 mg: 135 (48/87)	47	50 mg tid 100 mg tid	142 (53/89)	49	Placebo
					100 mg: 135 (57/78)
Talley et al[5], INT	2008	A	524	8	264 (86/178)	43	100 mg tid	260 (99/161)	43	Placebo
Talley et al[5], NOR	2008	A	626	8	308 (109/199)	43	100 mg tid	318 (96/222)	43	Placebo