Eosinophil associated genes in the inflammatory bowel disease 4 region: Correlation to inflammatory bowel disease revealed

Table 4 Gender specific difference

			Crohn’s disease						Ulcerative colitis
			Genotype distribution			Allelic frequency			Genotype distribution			Allelic frequency
	Age at diagnosis	Patients	EPX	ECP	ECP	EPX	ECP	ECP	EPX	ECP	ECP	EPX	ECP	ECP
	(yr)	CD/UC (n)	405	434	562	405	434	562	405	434	562	405	434	562
Female	≥ 40	80/71	NS	NS	NS	NS	0.043	0.034	NS	NS	NS	NS	NS	NS
	≥ 45	42/62	NS	0.009	0.013	NS	0.004	0.007	NS	NS	NS	NS	NS	NS
Male	≥ 40	77/85	NS	NS	NS	NS	NS	NS	0.048	0.025	0.008	0.026	0.024	0.045
	≥ 45	57/52	NS	NS	NS	NS	NS	NS	NS	0.01	0.009	NS	NS	NS

Difference (χ², P-values displayed) between the genotype distributions and allelic frequencies, related to age at diagnosis, in individuals with CD or UC compared with the healthy population. UC: Ulcerative colitis; CD: Crohn’s disease; NS: Not significant; EPX: Eosinophil protein X; ECP: Eosinophil cationic protein.