Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase

Table 4 Characteristics of 6 cases of drug-induced liver injury caused by glucocorticoids

Age/sex	Principal disease	Drug	Dose (mg/d)	Treatment duration (d)	Peak values					Follow-up
					ALT (U/L)	AST (U/L)	AP (U/L)	TB (mg/dL)	GGT (U/L)
20/F	SLE	MP	20-160	84	600	138	83	2.31	183	Recovered
36/F	Chronic glomerulonephritis	MP	32-40	17	1085	439	162	0.34	41	Improved
25/M	Brain trauma	MP	20	10	515	257	148	0.61	446	Improved
49/M	Brain trauma	MP	40	10	516	363	108	1.19	190	Improved
42/F	Drug eruption	MP	30-160	24	668	34	110	0.61	146	Improved
49/M	Brain tumor	DXM	5-15	12	602	282	231	0.52	424	Improved

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; AP: Alkaline phosphatase; TB: Total bilirubin; GGT: γ-glutamyl transpeptidase; F: Female; SLE: Systemic lupus erythematosus; MP: Methylprednisolone; DXM: Dexamethasone.