Incidence of human papilloma virus in esophageal squamous cell carcinoma in patients from the Lublin region

Table 4 Clinico-pathological characteristics of esophageal squamous cell carcinoma patients investigated from Lublin region

Characteristic	HPV positive		HPV high risk		HPV low risk
	n (%)	P value	n (%)	P value	n (%)	P value
Gender
Male	23 (46.9)	0.44351	2 (4.1)	0.02941	17 (34.7)	0.12541
Female	5 (71.4)		3 (42.9)		2 (28.6)
Age (yr)
> 50	25 (54.4)	0.72741	3 (6.5)	0.23321	18 (39.1)	0.22171
< 50	3 (30.0)		2 (20.0)		1 (10.0)
Macroscopic type
ULC	2 (20.0)	0.02932	0 (0.0)	0.11252	2 (20.0)	0.14482
INF	5 (83.3)		1 (16.7)		4 (66.7)
ULC/INF	15 (71.4)		3 (14.3)		9 (42.9)
PROT	6 (31.6)		1 (5.3)		4 (21.1)
Grading
G1	3 (75.0)	0.32342	1 (25.0)	0.26382	2 (50.0)	0.29112
G2	19 (44.2)		3 (7.0)		15 (34.9)
G3	6 (66.7)		1 (11.1)		2 (22.2)
Staging
II	11 (36.7)	0.27202	3 (10.0)	0.61062	6 (20.0)	0.35372
III	14 (73.7)		2 (10.5)		10 (52.6)
IV	3 (42.9)		0 (0.0)		3 (42.9)
Tumor
T2	11 (57.9)	0.34582	3 (15.8)	0.10132	7 (36.8)	0.31252
T3	15 (51.7)		1 (3.5)		11 (37.9)
T4	2 (25.0)		1 (12.5)		1 (12.5)
Nodes
N0	12 (48.0)	0.76041	3 (12.0)	0.24841	7 (28.0)	0.46261
N1	16 (51.6)		2 (6.5)		12 (38.7)

¹Mann-Whithey U test;

²Kruskal-Wallis test. HPV: Human papilloma virus; ULC: Ulcerative; INF: Infiltrative; PROT: Protruding.