Liver cold preservation induce lung surfactant changes and acute lung injury in rat liver transplantation

Figure 1 Representative lung tissue sections and histopathological scores. A: Sham group; B: 90-min group; C: 180-min group; D: PDTC group. Alveolar, perivascular and interstitial edema, neutrophil infiltration, atelectasis, disruption of alveolar and bronchiolar epithelial cells, and local hemorrhage aggravated with prolonged CPT; E: Lung histopathological scores in different groups. The scores in the CPT groups were significantly higher than that in the sham group, but lower than in the PDTC group. ^aP < 0.05 vs sham group; ^bP < 0.05 vs 45-min group. PDTC: Pyrrolidinedithiocarbamate; CPT: Cold preservation time.