Software for automated classification of probe-based confocal laser endomicroscopy videos of colorectal polyps

Table 3 Performance comparison between automated probe-based confocal laser endomicroscopy classification and off-line expert diagnosis of probe-based confocal laser endomicroscopy, for the differentiation between neoplastic and non-neoplastic colonic polyps

	Automated pCLE classification	Off-line expert diagnosis of pCLE
Accuracy
%	89.6	89.6
Fraction	121/135	121/135
Sensitivity
%	92.5	91.4
Fraction	86/93	85/93
Specificity
%	83.3	85.7
Fraction	35/42	36/42
Statistical significance between (1) and (2)
McNemar’s test, alpha = 0.05
Accuracy: (P, power)	(Not significant, 2.5%)
Sensitivity: (P, power)	(Not significant, 6.5%)
Specificity: (P, power)	(Not significant, 5.2%)
Statistical equivalence between (1) and (2)
Two-sided Z test
95% CI for accuracy	-0.073-0.073
95% CI for sensitivity	-0.068-0.089
95% CI for specificity	-0.18-0.13

pCLE: Probe-based confocal laser endomicroscopy.