Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22

doi:10.3748/wjg.v18.i36.5122

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Sep 28, 2012 (publication date) through Sep 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2012; 18(36): 5122-5128
Published online Sep 28, 2012. doi: 10.3748/wjg.v18.i36.5122

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Figure 4 Levels of interleukin 22 in lung tissue samples from rats in the sham operation, severe acute pancreatitis, and melatonin treatment groups. Levels of IL-22 at 1, 4 and 8 h after induction of SAP. Levels of IL-22 decreased with continued progression of SAP (P < 0.01). ^bP < 0.01 vs the SO group; ^dP < 0.01 vs the SO and SAP groups (n = 8 rats per group). SO: Sham operation; SAP: Severe acute pancreatitis; IL: Interleukin; Th: T helper cell; MT: Melatonin treatment.

Citation: Huai JP, Sun XC, Chen MJ, Jin Y, Ye XH, Wu JS, Huang ZM. Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22. World J Gastroenterol 2012; 18(36): 5122-5128
URL: https://www.wjgnet.com/1007-9327/full/v18/i36/5122.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i36.5122