Predictors of the outcomes of acute-on-chronic hepatitis B liver failure

Table 3 Laboratory tests after the first week of anti-hepatitis B virus therapy

	Survivors (n = 52)	Dead (n = 61)	P value
White blood cell count	6.50 (3.40)	9.35 (6.95)	< 0.001
(×103/cumm )
Hemoglobin (g/dL)	10.25 (1.95)	0.20 (3.70)	0.780
Platelet (×103/cumm)	92.50 (74.50)	79.50 (91.25)	0.356
Prothrombin time (s)	17.20 (4.85)	21.65 (9.35)	< 0.001
INR	1.96 (1.00)	2.87 (2.38)	< 0.001
Creatinine (mg/dL)	0.70 (0.50)	1.10 (1.35)	< 0.001
ALT (U/L)	95.50 (331.25)	115.50 (299.00)	0.238
Total bilirubin (mg/dL)	12.75 (9.60)	20.30 (15.20)	0.003
Direct bilirubin (mg/dL)	7.45 (7.85)	10.30 (8.60)	0.093
Albumin (g/dL)	3.00 (0.70)	2.80 (0.85)	0.098
Ammonia (μg/dL)	118.00 (96.00)	159.50 (223.00)	0.005
Serum sodium (mmol/L)	134.00 (8.00)	138.00 (8.00)	0.003
Serum potassium (mmol/L)	4.10 (0.90)	3.80 (1.00)	0.649
Serum chloride (mmol/L)	104.00 (14.00)	105.00 (18.00)	0.338
Serum calcium (mg/dL)	8.40 (1.25)	8.45 (1.43)	0.922
Serum magnesium (mg/dL)	1.80 (1.45)	2.30 (0.93)	0.216
MELD score	25.00 (7.00)	32.00 (12.00)	< 0.001
APACHE-II score	13.00 (10.00)	17.50 (9.00)	0.014

The median (interquartile range) is presented for continuous variables. P values were derived using the Mann-Whitney U test. MELD: Model for end-stage liver disease; APACHE-II: Acute Physiology and Chronic Health Evaluation II; INR: International normalized ratio; ALT: Alanine transaminase.