Primary biliary cirrhosis-specific autoantibodies in first degree relatives of Greek primary biliary cirrhosis patients

Table 5 Characteristics of antimitochondrial antibodies-positive relatives with abnormal liver enzymes

	Age(yr)	Proband disease	Relationship to the proband	AST/ALT (U/L)	ALP/γ-GT (U/L)	Symptoms
Patient A	44	PBC	Son	37/45	102/122	No
Patient B	47	PBC	Brother	23/18	65/104	No
Patient C	40	PBC	Son	37/90	67/154	No
Patient D	24	PBC	Daughter	60/165	136/61	Sicca + Hashimoto’s thyroiditis
Patient E	52	PSC	Sister	53/103	91/94	Hashimoto’s thyroiditis

AST: Aspartate aminotransferase (upper limit: 35 U/L); ALT: Alanine aminotransferase (upper limit: 40 U/L); γ-GT: Gamma-glutamyl transpeptidase (upper limit: 37 U/L); ALP: Alkaline aminophosphatase (upper limit: 104 U/L); PBC: Primary biliary cirrhosis; PSC: Primary sclerosing cholangitis.