Screening Helicobacter pylori genes induced during infection of mouse stomachs

doi:10.3748/wjg.v18.i32.4323

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Aug 28, 2012; 18(32): 4323-4334
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4323

Table 3 Helicobacter pylori in vivo induced genes

	Locus	Function or enzyme	Role in virulence
ivi-232	flhF	Regulation of flagella biosynthesis	Motility
ivi-122	fliA	Flagellar motor switch protein
ivi-121	fliM	Flagella motor switch protein
ivi-364	tlpc	Methyl-accepting chemotaxis protein
ivi-11	trxB	Thioredoxin reductase	Oxidative stress protection
ivi-134	nth1	Endonuclease III
ivi-322	ycf5	Cytochrome C biogenesis protein
ivi-352	sodB	Iron-dependent superoxide dismutase	Acid resistance
ivi-161	hsdM	DNA methyltransferase	Nucleic acid metabolism
ivi-162	hsdM/R	Type II restriction enzyme R and M protein
ivi-123	recG	ATP-dependent DNA helicase
ivi-351	priA	Primosome protein replication factor
ivi-361	tnpB	IS606 Transposase
ivi-171	lpxC	UDP-3-O-acyl N- acetylglucosamine deacetylase	Cell envelope structures
ivi-172	minC	Septum site directing protein
ivi-1722	murD	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthase
ivi-1721	murC	UDP-N-acetylmuramoyl alanine-D-glutamate ligase
ivi-363	murI	Glutamate racemase
ivi-321	fucT	Alpha 1, 3-fucosyltransferase
ivi-351	omp26	Outer membrane protein
ivi-112	pgi	Glucose-6-phosphate isomerase	Sugar metabolism
ivi-1132	rbfA	Ribosome binding factor A	Translation and regulation
ivi-1131	infB	Translation initiation factor IF-2
ivi-2721	cysS	Cysteinyl-tRNA synthetase	Protein and peptide synthesis
ivi-110	vacA	Vacuolating toxin	Virulence factors
ivi-362	cagA	Cytotoxin-associated gene
ivi-192	virB4	Type IV secretion system	Transport cagA protein
ivi-241		Predicted coding region HP0426	H. pylori hypothetical protein
ivi-242		Predicted coding region HP0427	H. pylori hypothetical protein
ivi-3101		Predicted coding region HP0423	H. pylori hypothetical protein
ivi-3102		Predicted coding region HP0424	H. pylori hypothetical protein

H. pylori: Helicobacter pylori.

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Citation: Singh A, Hodgson N, Yan M, Joo J, Gu L, Sang H, Gregory-Bryson E, Wood WG, Ni Y, Smith K, Jackson SH, Coleman WG. Screening Helicobacter pylori genes induced during infection of mouse stomachs. World J Gastroenterol 2012; 18(32): 4323-4334
URL: https://www.wjgnet.com/1007-9327/full/v18/i32/4323.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i32.4323

Singh A, Hodgson N, Yan M, Joo J, Gu L, Sang H, Gregory-Bryson E, Wood WG, Ni Y, Smith K, Jackson SH, Coleman WG. Screening Helicobacter pylori genes induced during infection of mouse stomachs. World J Gastroenterol 2012; 18(32): 4323-4334 [PMID: 22969195 DOI: 10.3748/wjg.v18.i32.4323]

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