Increased expression of chondroitin sulphate proteoglycans in rat hepatocellular carcinoma tissues

Figure 7 Immunochemical staining for biglycan in rat liver tissues. Biglycan positive staining was dark red. A and C: Control group; B, D and E: Hepatocellular carcinoma (HCC) model group. Long white arrow: Fibrous tissue septa; short black and white arrows: The cells are magnified in the small boxes; E: Areas in black and red boxes are magnified in left column; F: Comparison of the average integrated optical density (IOD) in biglycan positive staining in liver tissues between the control and HCC model groups (^bP < 0.001). IOD/area: Integrated optical density per stained area.