Matrix metalloproteinases in the restorative proctocolectomy pouch of pediatric ulcerative colitis

Table 3 Expression profiles of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinase in ulcerative colitis samples

	Number of positive samples	mean±SEM1
MMP-3
Epithelium	22	0.93 ± 0.114
Stroma	20	1.25 ± 0.183
MMP-7
Epithelium	28	1.36 ± 0.092
Stroma	27	1.89 ± 0.149
MMP-8
Epithelium	0	0.00 ± 0.000
Stroma	1	0.04 ± 0.036
MMP-9
Epithelium	0	0.00 ± 0.000
Stroma	9	0.32 ± 0.090
MMP-12
Epithelium	20	0.75 ± 0.098
Stroma	24	1.46 ± 0.141
MMP-26
Epithelium	0	0.00 ± 0.000
Stroma	3	0.11 ± 0.060
TIMP-1
Epithelium	0	0.00 ± 0.000
Stroma	0	0.00 ± 0.000
TIMP-2
Epithelium	23	0.89 ± 0.094
Stroma	23	1.75 ± 0.203
TIMP-3
Epithelium	23	1.04 ± 0.120
Stroma	28	2.39 ± 0.130
Histology
Neutrophils		0.85 ± 0.154
Lymphocytes		1.07 ± 0.185
Eosinophils		1.04 ± 0.167
Villus atrophy		1.19 ± 0.227
Grade		1.95 ± 0.203

¹mean calculated from values: 0 = less than 20 positive cells; 1 = 20-50 positive cells; 2 = 50-200 positive cells; 3 = over 200 positive cells; Grade: Grade of inflammation; MMPs: Matrix metalloproteinases; TIMP: Tissue inhibitor of matrix metalloproteinase.