Endoscopic and clinicopathologic characteristics of early gastric cancer with high microsatellite instability

Table 3 Logistic regression analysis of endoscopic and clinicopathologic features of high microsatellite instability early gastric cancer

	OR	95% CI		P value
		Lower	Upper
Endoscopic factors
Elevated gross type (I or IIa)	4.38	2.40	8.01	< 0.001
Antral location	3.99	2.12	7.52	< 0.001
Intestinal metaplasia (moderate-to-severe)	1.55	0.87	2.75	0.139
Mucosal atrophy (moderate-to-severe)	1.91	1.05	3.47	0.033
Clinicopathologic factors
Female sex	2.77	1.53	4.99	< 0.001
Age ≥ 70 years	3.30	1.57	6.92	0.002
Histologic differentiation (well or moderately)	2.35	1.27	4.34	0.007
Lauren classification (intestinal type)	2.34	1.15	4.76	0.019
Submucosal invasion	1.61	0.91	2.87	0.103
Less signet ring cell component	2.44	1.02	5.86	0.046
Mucinous component	5.06	1.27	20.17	0.022
Lymph node metastasis	1.86	0.81	4.25	0.144
Lymphovascular invasion	1.71	0.84	3.47	0.137
Lymphoid stromal reaction (moderate-to-severe)	3.95	1.59	9.80	0.003
Co-existing underlying adenoma	2.66	1.43	4.95	0.002
Synchronous EGC or adenoma	2.65	1.16	6.07	0.021

OR: Odds ratios; CI: Confidence intervals; EGC: Early gastric cancer.