Acute pancreatitis in aging animals: Loss of pancreatitis-associated protein protection?

Figure 6 Immunohistochemistry for pancreatitis-associated proteins (40×) in a young control animal without pancreatitis (A) compared to pancreatitis-associated protein 1 (B) and pancreatitis-associated protein 2 (C) in young animals 24 h after sodium taurocholate pancreatitis. No staining is seen in controls, uniform brown colored staining is seen for pancreatitis-associated protein (PAP)1 (B). Preparation of the slides was done side by side. A different, heterogenous pattern of staining is seen for PAP2 (C). Note that islets of Langerhans (arrows) do not stain at all for PAPs in normal animals or animals with acute pancreatitis.