Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice involving cholinergic mechanism

Figure 3 Effect of co-administered mangiferin on delayed gastrointestinal transit induced by morphine, ondansetron, and capsaicin in mice. A: Morphine (2.5 mg/kg, sc); B: Ondansetron (3 mg/kg, ip); C: Capsaicin (0.3 mg/kg, po) induced gastrointestinal transit-delay. Each column represents mean ± SEM (n = 8). ^aP < 0.05 vs vehicle control group; ^cP < 0.05 vs respective morphine/ondansetron/capsaicin; ^eP < 0.05 vs mangiferin alone group.