Stem cell factor-mediated wild-type KIT receptor activation is critical for gastrointestinal stromal tumor cell growth

Figure 5 Stem cell factor inhibits gastrointestinal stromal tumor cell apoptosis in vitro. Representative flow cytometric contour of annexin V-fluorescein isothiocyanate (FITC)/propidium iodide (PI) dual-colour flow cytometry after 12 h of treatment with exogenous stem cell factor (SCF) or KIT immunoblocking antibody. The lower right quadrant represents early apoptotic cells. The data are presented as the mean ± SD (n = 4 for each). ^aP < 0.01 vs untreated cells.