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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 7, 2012; 18(21): 2668-2673
Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2668
Published online Jun 7, 2012. doi: 10.3748/wjg.v18.i21.2668
Table 2 Association risk and frequencies of T and A alleles of interleukin-8 -251T>A genotypes with colorectal cancer susceptibility
| Patients | Controls | OR (95% CI) | P value | |
| IL-8 genotype | ||||
| Wild type -251TT | 40 (15.69) | 54 (21.18) | [1] (Ref.) | - |
| Hetero -251TA | 183 (71.76) | 189 (74.12) | 1.307 (0.808-2.117) | 0.250 |
| Variant -251AA | 32 (12.55) | 12 (4.7) | 3.600 (1.550-8.481) | 0.001 |
| Allele | ||||
| Wild type | 263 (51.6) | 297 (58.2) | 0.76 (0.59-0.97) | - |
| Variant | 247 (48.4) | 213 (41.8) | 1.32 (1.03-1.69) | 0.003 |
- Citation: Mustapha MA, Shahpudin SNM, Aziz AAA, Ankathil R. Risk modification of colorectal cancer susceptibility by interleukin-8 -251T>A polymorphism in Malaysians. World J Gastroenterol 2012; 18(21): 2668-2673
- URL: https://www.wjgnet.com/1007-9327/full/v18/i21/2668.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i21.2668