Role of bone marrow-derived mesenchymal stem cells in a rat model of severe acute pancreatitis

Table 5 Comparison of serum malonaldehyde, superoxide dismutase levels, interleukin-6, interleukin-10 and tumor necrosis factor-α measured at various time points after injecting either mesenchymal stem cells or saline into rats after establishing an severe acute pancreatitis model (n = 36, mean ± SD)

Index	Group	Post-mesenchymal stem cells or saline injection (h)
		6	24	72
Malonaldehyde (nmol/mL)	Severe acute pancreatitis group	4.89 ± 0.97	5.20 ± 1.21	4.43 ± 0.42
	Severe acute pancreatitis + mesenchymal stem cells group	3.68 ± 0.38a	3.89 ± 0.59a	3.36 ± 0.98a
Superoxide dismutase (U/mL)	Severe acute pancreatitis group	43.16 ± 6.94	48.13 ± 3.93	45.83 ± 4.72
	Severe acute pancreatitis + mesenchymal stem cells group	48.05 ± 3.83	61.29 ± 7.81b	50.75 ± 7.59
Interleukin-6 (pg/mL)	Severe acute pancreatitis group	107.70 ± 13.08	128.52 ± 8.52	134.06 ± 13.12
	Severe acute pancreatitis + mesenchymal stem cells group	90.16 ± 9.55a	107.33 ± 12.13b	143.24 ± 12.11
Interleukin-10 (pg/mL)	Severe acute pancreatitis group	31.08 ± 6.64	45.02 ± 4.28	40.11 ± 8.39
	Severe acute pancreatitis + mesenchymal stem cells group	40.84 ± 7.05a	52.08 ± 5.79a	41.76 ± 3.37
TNF-α (pg/mL)	Severe acute pancreatitis group	106.15 ± 9.01	132.62 ± 8.64	122.42 ± 13.44
	Severe acute pancreatitis + mesenchymal stem cells group	91.47 ± 10.00a	119.47 ± 10.83a	110.91 ± 9.92

^aP < 0.05,

^bP < 0.01 vs the severe acute pancreatitis group. TNF-α: Tumor necrosis factor-α.