Effect of soy protein supplementation in patients with chronic hepatitis C: A randomized clinical trial

Table 7 Logistic regression model for factors predictive of homeostasis model assessment of insulin resistance in patients with hepatitis C virus after 12 wk of protein supplementation

	Bivariate analysis		Multivariate analysis
	Crude OR (95% IC)	P value	Adjusted OR1 (95% IC)	P value
Groups
Control-casein	1		1
Intervention-soy	0.90 (0.47-1.70)	0.745	1.92 (0.80-4.83)	0.15
Stage of fibrosis
F0/F1/F2	1		1
F3/F4	4.21 (1.99-9.19)	0.0002	5.25 (2.17-13.67)	0.0004
Alanine aminotransferase
1.5 times below ULN	1		1
1.5 times above ULN	2.22 (1.16-4.30)	0.017	3.26 (1.30-8.71)	0.014
Marital status
Married	1		1
Single, widowed or divorced	0.52 (0.24-1.07)	0.081	0.24 (0.08-0.65)	0.007
Waist circumference2
Adequate	1		1
Inadequate	2.62 (1.37-5.16)	0.004	5.57 (2.23-15.27)	0.0004

¹Adjusted for the other variables shown in the table;

²Adequate waist circumference: ≤ 80 cm for women and ≤ 94 cm for men; ULN: Upper limit of normal; OR: Odd ratio; 95% IC: 95% confidence interval.