Hepatocellular carcinoma in Budd-Chiari syndrome: A single center experience with long-term follow-up in South Korea

Table 3 Comparison of baseline clinical characteristics between hepatocellular carcinoma group and non hepatocellular carcinoma group

Variables	HCC(n = 17)	Non HCC(n = 50)	P value
Age (yr)	47 ± 11	47 ± 18	0.863
Gender (male)	10 (58.8)	24 (48)	0.441
Obstructive site			0.264
IVC	15 (88.2)	41 (82)
Hepatic vein	2 (11.8)	3 (6)
Combined	0 (0)	6 (12)
Alcohol consumption			0.329
None	6 (35.3)	26 (52.0)
Social	4 (23.5)	11 (22.0)
Heavy (> 80 g/d)	7 (41.2)	13 (26.0)
Positive for HBsAg	0 (0)	3 (6.0)	0.554
LC at diagnosis	14 ( 82.4)	40 (80.0)	0.832
Decompensate LC symptoms	8 (47.1)	15 (28.0)	0.148
Child Pugh A/B/C	5/7/2	20/16/4	0.647
MELD score	11 ± 6	11 ± 6	0.778
Follow up period (mo)	103 ± 146	103 ± 160	0.648
Length of obstruction (cm)	1.0 ± 2.5	2.0 ± 4.4	0.144
HVPG (mmHg)	21 ± 12	14 ± 7	0.019
Laboratory data
ALT (IU/L)	21 ± 21	18 ± 14	0.160
Bilirubin (mg/dL)	1.5 ± 1.9	1.3 ± 1.3	0.521
Albumin (g/dL)	3.6 ± 0.85	3.8 ± 0.72	0.245
Hemoglobin (g/dL)	12.5 ± 4.1	12.3 ± 2.3	0.897
Platelet count (k/μL)	97 ± 59.5	113 ± 80.7	0.559
Creatinine (mg/dL)	0.9 ± 0.14	0.85 ± 0..24	0.798
PT (%)	71 ± 31	74 ± 22	0.756
Survival (%)			< 0.001
5 yr	79	93.4
10 yr	43.1
15 yr	21.5	74.7

Data were expressed as median ± IQR or n (%). HCC: Hepatocellular carcinoma; IVC: Inferior vena cava; LC: Liver cirrhosis; MELD: Model for End-Stage Liver Disease; HVPG: Hepatic venous pressure gradient; ALT: Alanine aminotransferase; PT: Prothrombin time; IQR: Interquartile range.