Propofol vs midazolam plus fentanyl for upper gastrointestinal endomicroscopy: A randomized trial

Table 5 Quality of sedation

	P group	M/F group	P value
Sedation time (min)	3.22 ± 1.70	4.47 ± 2.40	0.002
Procedure time (min)	25.00 ± 6.51	28.45 ± 8.04	0.028
Adverse events			0.339
Hypoxemia	0	0
Hypotension	3	1
Bradycardia	0	0
Patient assessment
Satisfaction	10 (10–10)	10 (9–10)	0.105
Pain or discomfort	0 (0–0)	0 (0–1)	0.145
Intraprocedural recall	0 (0–0)	0 (0–1)	0.006
Willingness to repeat (n)			0.559
Lighter	5	4
Deeper	4	7
Same level	40	40
Endoscopist assessment
Satisfaction with sedation	10 (9–10)	9 (8–10)	0.003
Patient cooperation	4 (4–4)	4 (3–4)	0.002
Quality of endoscopy	4 (4–4)	4 (3–4)	0.018
Level of sedation			0.014
Apparently inadequate	0	3
Inadequate	7	16
Adequate	41	31
Oversedated	1	1
Assistant satisfaction	9 (9–10)	8 (7–10)	0.001
Anesthetist satisfaction	9 (9–10)	7 (5–8)	< 0.001

Continuous variables were given as the mean ± SD. Non-normally distributed variables were expressed as median (the 1st-3rd interquartile) and compared with the Mann-Whitney U test. P group: Propofol group; M/F group: Midazolam plus fentanyl group.