Prognostic significance of PTEN, Ki-67 and CD44s expression patterns in gastrointestinal stromal tumors

Figure 1 Examples of the selected markers expressed in gastrointestinal stromal tumor. A: The tumor cells were strongly positive for CD117 with diffuse membrane staining; B: Nuclear positivity of Ki-67 in the tumor cells; C: Nuclear positivity of PTEN in gastrointestinal stromal tumor; D: CD44s was diffusely positive in tumor cell membrane; E: Matrix metalloproteinase 9 was diffusely positive in cytoplasm; F: TIMP-1 was diffusely positive in cytoplasm. Immunostains counterstained with hematoxylin-eosin, original magnifications × 200.