Vitamin D receptor gene polymorphisms and colorectal cancer risk: A systematic meta-analysis

doi:10.3748/wjg.v18.i14.1672

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 14

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (4548)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-2) series, Tables (1-3) series.

Item

Count

PDF

435

HTML

3768

Figures (1-2)

144

Tables (1-3)

201

Sum=4548

Apr 14, 2012 (publication date) through May 19, 2024

Times Cited of This Article

Times Cited (61)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Brief Article

World J Gastroenterol. Apr 14, 2012; 18(14): 1672-1679
Published online Apr 14, 2012. doi: 10.3748/wjg.v18.i14.1672

Table 2 Summary odds ratios and 95% CI in the vitamin D receptor gene

SNP	Model	Total No. cases	Total No. controls	OR (95% CI)¹	P value²	P value³
Cdx-2	Codominant (CC vs cc)	152/1561	146/1820	1.25 (0.98-1.59)	0.07	0.26
	Codominant (Cc vs cc)	926/2487	982/2802	1.09 (0.97-1.22)	0.15	0.64
	Codominant (C vs C)	1230/4048	1279/4622	1.10 (1.01-1.21)	0.03	0.47
	Dominant (CC + Cc vs cc)	1078/1561	1208/1820	0.98 (0.88-1.09)	0.72	< 0.001
	Recessive (CC vs Cc + cc)	152/2487	146/2802	1.22 (0.96-1.54)	0.10	0.23
FokI	Codominant (ff vs FF)	1844/5068	2377/5982	0.94 (0.87-1.01)	0.09	0.001
	Codominant (Ff vs FF)	6189/11 257	7583/13 565	0.98 (0.93-1.03)	0.34	0.001
	Codominant (f vs F)	9867/16 320	12 190/19 329	0.97 (0.94-1.00)	0.07	< 0.001
	Dominant (ff + Ff vs FF)	8033/5068	9960/5982	0.96 (0.92-1.01)	0.15	< 0.001
	Recessive (ff vs FF + Ff)	1844/11 257	2377/13 565	0.95 (0.89-1.02)	0.13	0.01
BsmI	Codominant (BB vs bb)	1512/3838	1817/4122	0.87 (0.80-0.94)	< 0.001	0.65
	Codominant (Bb vs bb)	4733/8571	5303/9425	0.94 (0.88-0.99)	0.03	0.64
	Codominant (B vs b)	7757/12 409	8937/13 577	0.93 (0.90-0.97)	< 0.001	0.85
	Dominant (BB + Bb vs bb)	6245/3838	7120/4122	0.92 (0.87-0.97)	0.003	0.84
	Recessive (BB vs Bb + bb)	1512/8571	1817/9425	0.90 (0.84-0.97)	0.006	0.28
ApaI	Codominant (AA vs aa)	748/578	1004/603	0.85 (0.73-0.99)	0.03	0.06
	Codominant (Aa vs aa)	1378/1956	1593/2196	0.91 (0.79-1.04)	0.18	0.39
	Codominant (A vs a)	2944/2534	3601/2799	0.92 (0.85-0.99)	0.02	0.04
	Dominant (AA + Aa vs Aa)	2161/578	2597/603	0.89 (0.78-1.01)	0.07	0.12
	Recessive (AA vs Aa + aa)	783/1956	1004/2196	0.89 (0.80-1.00)	0.05	0.21
TaqI	Codominant (tt vs TT)	382/1112	398/1320	1.05 (0.89-1.24)	0.58	0.07
	Codominant (Tt vs TT)	1086/2198	1298/2618	0.93 (0.83-1.05)	0.23	0.30
	Codominant (t vs T)	1850/3310	2098/3938	0.99 (0.92-1.08)	0.86	0.10
	Dominant (tt + Tt vs TT)	1468/1112	1696/1320	0.95 (0.85-1.07)	0.42	0.37
	Recessive (tt vs Tt + TT)	382/2198	398/2618	1.07 (0.92-1.25)	0.38	0.01

¹Based on fixed effects model;

²Test for overall effect;

³Test for heterogeneity. OR: Odds ratios.

Citation: Bai YH, Lu H, Hong D, Lin CC, Yu Z, Chen BC. Vitamin D receptor gene polymorphisms and colorectal cancer risk: A systematic meta-analysis. World J Gastroenterol 2012; 18(14): 1672-1679
URL: https://www.wjgnet.com/1007-9327/full/v18/i14/1672.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i14.1672