Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis

Table 1 The relationship between receptor 2 expression and clinicopathological features in hepatocellular carcinomas

Variables	n	Ror2 immunoreactivity		P
		Low	High
Gender				0.890
Male	77	56	21
Female	8	6	2
Age (yr)				0.725
< 53 (median)	38	27	11
≥ 53	47	35	12
Serum AFP level (μg/L)				< 0.001
< 30	30	14	16
≥ 30	55	48	7
HBsAg				0.862
Positive	73	53	20
Negative	12	9	3
Tumor size (cm)				0.116
≤ 2	3	1	2
> 2	82	61	21
Histological grade				0.090
Well differentiated	9	7	2
Moderately differentiated	60	40	20
Poorly differentiated	16	15	1
Liver cirrhosis				0.553
Present	56	42	14
Absent	29	20	9
T classification				< 0.001
T1	3	1	2
T2	30	14	16
T3	40	36	4
T4	12	11	1
Total	85	62	23

AFP: α-fetoprotein; HBsAg: Hepatitis B surface antigen; Ror2: Receptor tyrosine kinase-like orphan receptor 2.