Intravenous injection of mesenchymal stem cells is effective in treating liver fibrosis

Figure 5 Real-time polymerase chain reaction analysis for detecting the expression difference of cytokines, growth factors and interleukin, which are involved in liver fibrosis progression, among different mesenchymal stem cell transplanted modalities. The histogram shows the relative expression level for intravenous, intrahepatic and intraperitoneal injections. Data represent the mean ± SE, ^aP < 0.05. A and I: The expression of mmp2 and il10 in intravenous injection was significantly higher than other injection modalities; F, J, C, H and L: The expression of il1β, tnfα, timp1, il6 and tgfβ1 was significantly lower in intravenous injection than others; E, B, G, K and D: The expression of pdgf, mmp9, il2, hgf, infγ and hgf was not significantly different among the three mesenchymal stem cell injection modalities.