Is hepatic neoplasm-related pyogenic liver abscess a distinct clinical entity?

Table 2 Laboratory findings and radiological features of patients with/without hepatic neoplasm-associated pyogenic liver abscess n (%)

Laboratory parameters	HN group(n = 35)	Non-HN group(n = 283)	P value
Hemoglobin (mean, g/dL)	10.0	11.3	0.22
White cell count (mean, 109/L)	18.9	16.8	0.13
ESR (mean, mm/h)	82.0	78.9	0.84
CRP (mean, mg/L)	120.0	141.8	0.56
Albumin (mean, g/L)	27.1	29.6	0.56
Total bilirubin (mean, mol/L)	43.3	30.0	0.05
Alanine aminotransferase (mean, U/L)	64.1	84.1	0.16
Hba1c (mean, %)	10.3	9.1	0.41
Bacteremia	13 (37.1)	120 (42.4)	0.27
Radiological features
Size (cm, mean ± SD)	6.8 ± 3.1	6.1 ± 3.0	0.19
Site
Right lobe	22 (62.9)	156 (55.1)	0.19
Solitary/multiple	15 (43)/ 7 (20)	133 (47)/ 23 (8.1)
Left lobe	7 (20)	82 (29)	0.13
Solitary/multiple	5 (14.3)/ 2 (5.7)	73 (25.8)/ 9 (3.2)
Bilobar	3 (8.6)	37 (13.1)	0.22
Echogenicity
Hypoechoic	31 (88.6)	256 (90.5)	0.36
Hyperechoic/heterogenous	4 (11.4)	27 (9.5)	0.37
Thicken wall	13 (37.1)	55 (19.4)	< 0.01
Rim enhancement	26 (74.3)	176 (62.2)	0.08
Septal lobulation	27 (77.1)	164 (58.0)	< 0.02
Aerobilia	7 (25.9)	16 (5.5)	< 0.01
Fluid/gaseous cavitation	33 (94.3)/ 6 (17.1)	243 (85.9)/ 21 (7.8)	0.08/ 0.03
Portal thrombophlebitis	4 (11.4)	5 (1.8)	< 0.01
Subcapsular rupture of the abscess	2 (5.7)	16 (5.6)	0.49

HN: Hepatic neoplasm; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate.